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KMID : 0381019940270080819
Korean Journal of Nutrition
1994 Volume.27 No. 8 p.819 ~ p.827
Effects of Buckwheat on Organ Weight, Glucose and Lipid Metabolism in Streptozotocin-Induced Diabetic Rats
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Abstract
The present study was undertaken to evaluate the effects of 50% buckwheat diet on the body weight, organ weight, urine albumin, urine glucose, glucose, plasma glucose and plasma lipid in normal rats and diabetic rats treated with streptozotocin
(STZ)
The food intake, body weight, the level of urine glucose in diabetic buckwheat groups were not significantly different with diabetic control group The level of urine albumin was lower in raw and steam buckwheat group than in the diabetic Compared
to the
normal control group, liver and kidney weights heavier in the diabetic groups. Pancreas weight was heavier diabetic buckwheat groups than in normal and diabetic control groups. Fasting plasma glucose level of diabetic buckwheat groups
significantly
decreased by 18-37% compared with the diabetic control group. Plasma triglyceride level of diabetic buckwheat groups significantly decreased by 34-50% compared with the diabetic control group. Plasma total cholesterol level of diabetic buckwheat
groups
decreased by 15-27% compared with the diabetic control group. The level of HDL-cholesterol was not affected by buckwheat diet. These results indicate that buckwheat is an effective therapeutic regimen for the control of metabolic derangements in
diabetics.
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